JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF HEAD NECK & SPINE SURGERY Abstract Professional sport activities or work may exert considerable stress on the spine. We aimed to assess the effects of loading on the deformation of the vertebral body of the twelfth thoracic vertebra (T12) and the lumbar vertebrae (L1-L5), which are subjected to considerable stress in basketball players. A total of 20 basketball players were assigned to one of two groups, based on their experience with playing basketball: under 5 years, junior group; over 5 years, senior group. All participants underwent magnetic resonance imaging; the relevant geometric variables were measured using specialized software, and the outcome measures were calculated using specific formulas; the outcome measures were compared between the junior and senior groups. The results indicated a significant difference between the two groups with respect to the compression deformity ratio at four levels (T12, L1, L2, and