JuniperPublishers_Head Neck & Spine Surgery

  Juniper Publishers-Open Access  Journal of Head Neck & Spine Surgery Role of MiRNAs in Oral Cancer Authored by   Bin Guo Abstract Oral cancer, one of the most common cancers worldwide, exhibits high mortality and morbidity rates. The incidence rate of oral cancer is high in developing countries, especially in Asian countries. MiRNAs are non-coding RNAs with significant regulatory functions, such as mRNA degradation or translation inhibition. Understanding of the tumorigenesis of oral cancer has significantly progressed at multiple levels. MiRNAs play an important role in oral tumors and have been associated with specific oral cancer phenotypes, such as tumorigenesis, progression, recurrence, or postoperative survival. MiRNAs exist stably in common body fluids and are thus ideal biomarkers for oral cancer. The miRNA profiles hallmark a potential diagnostic value for detection of oral cancer and potentially malignant disorders. In this review, we will summarize our cu

  Juniper Publishers-Open Access  Journal of Head Neck & Spine Surgery Monitoring Evoked Potentials in Order to Guarantee Integrity During Spine Surgery Authored by Diego Liberati Opinion As early as in 1986 during my first visiting scholarship in New York University thanks to a NATO grant, together with E.R. John, then director of the Brain Research Labs, we were monitoring via Evoked Potentials the integrity of the facial nerve of people undertaking fossa tumor surgery in order to early detect heating of the facial due to laser surgery in the close cavity and thus stop for a while the surgeon in order to prevent face deformation after surgery, the main uncomfortable drawback of such surgery. My contribution was to develop and apply my single-sweep Autoregressive analysis [1-5] to make detection as early as one second delay instead of more than a minute needed with conventional averaging. The approach enjoyed quite a success: did present its refinement to a conferen

  Juniper Publishers-Open Access  Journal of Head Neck & Spine Surgery Cochlear Endoscopy in Cochlear Implantation of a X-Linked Stapes Gusher Syndrome Authored by Jennifer Ha Abstract A 12-year-old boy with a five-year history of bilateral sensorineural hearing loss and X-linked stapes gusher syndrome developed progressive left-sided hearing loss. The pre-operative computed tomography of the temporal bone showed a bulbous internal auditory canal with a dysplastic cochlea and no apparent modiolus. A 1.3mm salivary endoscope was placed at the cochlear entrance to assess the intracochlear anatomy. This revealed membranous structures of the cochlea without direct communication to the internal auditory canal. We advocate for the use of cochlear endoscopy to better delineate inner ear anatomy, which will influence the implant selection and potentially hearing outcomes in patients. Keywords: MCochlear endoscopy; Otoendoscopy; X-linked stapes gusher syndrome; Cochlear implan

  Juniper Publishers-Open Access  Journal of Head Neck & Spine Surgery Delayed Progressive Cauda Equina Syndrome after Transverse Sacral Fracture: A Case Report Authored by Meni Mundama Abstract Transverse sacral fractures are infrequent injuries that often cause neurological impairment referred to as cauda equine syndrome. To the best of our knowledge, the onset of neurological symptoms can be delayed up to 2 months. We report a case of isolated transverse sacral fracture through S2-S3 which caused minor symptoms after 6 days. Major neurological disability appeared with a 3 months delay. A limited laminectomy was performed with good clinical results. The 3 months delay appeared to be the longest compared to available literature. Keywords: Transverse sacral fracture; Laminectomy; Caudaequina syndrome; Delay Introduction Transverse sacral fractures are rare. They occur after low or high energy trauma, with clinical manifestat

    Juniper Publishers-Open Access  Journal of                  Head Neck & Spine Surgery Stem Cells to Improve the Wound Healing Authored by Silvana Bellini Vidor Abstract The cellular therapy using Mesenchymal Stem Cells, specially its two subtypes - Bone-marrow Mesenchymal Stem Cells and Adipose Derived Stem Cells - can benefit by virtue of the possibility of differentiating in specialized cells that secrete and suppress growing factors and cytokines necessary in the lesion niche. When attracted by the pro-inflammatory sinalization of the lesion, they act using the paracrine signaling, decreasing the inflammation, increasing the angiogenesis and the cell migration and proliferation. The development in the researches regarding the association of the application of MSCs, with reconstructive surgery practices, leads to effective future results that can bring more benefits to the clinic practice of this field. This paper has the objective of briefly reviewing the literat

  Juniper Publishers-Open Access  Journal of                 Head Neck & Spine Surgery Acute Calcific Prevertebral Tendinitis Nonvisible in Plain Radiograph Authored by Ick Soo Choi Abstract Calcific tendinitis of the longus colli is an inflammatory disease caused by calcium hydroxyapatite crystal deposition in the longus colli tendon of the prevertebral space. The typical imaging characteristics of this entity are calcifications on the longus colli tendons at the C1-2 level and fluid collection in the retropharyngeal space in plain radiograph. Usually, calcific lesion can be detected by plain radiograph. We introduce 2 case of prevertebral calcific tendinitis nonvisible in plain radiograph, but the diagnosis was confirmed on computerized tomography. Keywords: Tissue plasminogen activator; Hemorrhage; Stroke; Blepharoplasty; Ectropion Ischemic stroke; Complications; Treatment. Introduction