JuniperPublishers_Head Neck & Spine Surgery

  Juniper Publishers-Open Access  Journal of Head Neck & Spine Surgery Sequential Delivery of Growth Factors from Hydrolytically Degradable Silica-Based Nanoparticles for Cartilage Tissue Engineering Authored by Danial Barati Abstract Articular cartilage shows a very limited self-healing capability due to it's a vascular structure. It has been reported that sequential supplementation of various growth factors such as bone morphogenic protein 7 (BMP-7), transforming growth factor-beta 1 (TGF-01) and insulin-like growth factor-I (IGF-I) play critical roles in reconstruction of articular cartilage tissue. The objective of this work is to design a drug delivery system which facilitates the controlled sequential delivery growth factors to maximize the extent of chondrogenic differentiation of mesenchymal stem cells and consequently reconstruction of damaged cartilage tissue. Surface-modified silica nanoaprticles (SNs) with short segments of lactide (L) and glycolid...

  Juniper Publishers-Open Access  Journal of Head Neck & Spine Surgery Study of Laryngotracheal Stenosis and its Management in 25 Cases Authored by L Sudarshan Reddy Abstract Introduction: Laryngotracheal stenosis is a complex problem resulting most often from intubation, trauma, or autoimmune disease. In this modern era, airway trauma has increased by considerable number owing to increased ventilator care in many emergency situations [ 1 ]. Anaesthetist's timely intubation saves the life of a patient but he must also be able to foresee the chaotic life of a prolongedly intubated patient who might develop stenosis. Objectives of the study: Clinical study of LTS was done to observe the various etiological causes for it and major concentration was towards the post intubational stenosis. With increasing ventilatory support for varied reasons in present day intensive care setup, the incidence of stenosis following intubation has equally increase. Management of...

  Juniper Publishers-Open Access  Journal of                 Head Neck & Spine Surgery Ticks in the External Auditory Canal: A Common Situation in Rural Areas Authored by Muhammet Recai Mazlumoglu Abstract Objective: Foreign bodies in the external auditory canal generally occur in children, and are generally inert. Ticks constitute live foreign bodies. This is important, because ticks are vectors of many diseases, including Crimean Congo hemorrhagic fever. This article throw as light into a clinical problem seen frequently especially in rural population. Material and Method: Patients living in rural areas diagnosed with ticks in the external auditory canal were retrospectively studied. Twenty- one patients treated in otorhinolaryngology clinic in the Northeast Anatolian region of Turkey were examined in terms of demographic and seasonal features, diagnosis, treatment, and follow-up. Results: The usual c...

  Juniper Publishers-Open Access  Journal of Head Neck & Spine Surgery Unilateral Bleeding Polyp in a Child: Lobular Capillary Hemangioma Authored by Sourabha Kumar Patro Abstract Epistaxis, though being common, always attracts special attention from medical professionals due to the nature of bleeding involved in the process. Children presenting with unilateral epistaxis warn otolaryngologists as the cause can vary from nasal foreign bodies to life threatening hemangiomas and angiofibromas. We present a rare case of lobular capillary hemangioma originating from nasal septum in a child who presented with episodes of profuse bleed. Early diagnosis and management with total excision was awarding. The occurrence is rare, however it should be in the differential diagnoses of unilateral nasal bleed in outpatient and emergency settings and strong suspicion is warranted. Keywords: Unilateral bleeding polyp in children; Nasal bleeding polyp; Unilateral nasal b...

  Juniper Publishers-Open Access  Journal of Head Neck & Spine Surgery Ameloblastic Carcinoma - Secondary Type, A Rare Case Report and Distinction from Malignant Ameloblastoma Authored by   Sauvik Singha  Abstract Ameloblastic Carcinoma (AC) primarily is an aggressive odontogenic tumour, which histologically consist of features of both ameloblastoma and carcinoma. This requires more aggressive surgical approach then its benign counterpart. Malignant Ameloblastoma (MA) microscopically appears benign but shows metastasis. The authors reported an extremely rare secondary type of Mandibular Ameloblastic Carcinoma of a 50 year old Indian male with a complaint of swelling, trismus, significant bone resorption with tooth mobility. This article discussed about the clinical features, radiographic features, management, and histological characteristics of AC and its distinction from MA. Introduction Ameloblastic Carcinoma...